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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC7
All Species:
4.55
Human Site:
S121
Identified Species:
11.11
UniProt:
Q8N3Z6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3Z6
NP_115602.2
543
63052
S121
E
N
A
H
G
L
S
S
S
L
Q
S
N
E
L
Chimpanzee
Pan troglodytes
XP_001169534
543
63034
S121
E
N
A
H
G
L
S
S
S
L
Q
S
N
E
L
Rhesus Macaque
Macaca mulatta
XP_001114863
543
63168
A121
E
N
A
F
G
P
S
A
S
L
Q
S
N
E
L
Dog
Lupus familis
XP_538733
544
63251
A120
E
K
T
Q
S
P
P
A
S
L
H
S
N
K
L
Cat
Felis silvestris
Mouse
Mus musculus
B1AX39
541
62982
P118
A
E
E
K
T
Q
S
P
A
T
S
H
S
N
K
Rat
Rattus norvegicus
B1WC15
542
63308
P118
A
Q
E
K
T
Q
S
P
A
T
P
R
S
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509565
566
65060
R133
I
I
A
H
S
S
L
R
S
K
A
S
T
V
E
Chicken
Gallus gallus
XP_424418
619
69362
P192
K
A
T
E
R
N
A
P
Y
P
A
G
S
D
R
Frog
Xenopus laevis
A1L2T6
563
64391
P137
G
P
C
S
H
S
T
P
K
V
S
A
P
Q
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199064
921
104738
D190
K
T
S
D
D
D
D
D
K
T
K
V
T
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.3
73.5
N.A.
64.8
64.8
N.A.
54.5
36.5
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
22.1
Protein Similarity:
100
99.6
97.6
82.1
N.A.
77.1
76.9
N.A.
69.7
52
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
34.6
P-Site Identity:
100
100
80
40
N.A.
6.6
6.6
N.A.
26.6
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
53.3
N.A.
20
20
N.A.
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
40
0
0
0
10
20
20
0
20
10
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
10
10
10
0
0
0
0
0
10
0
% D
% Glu:
40
10
20
10
0
0
0
0
0
0
0
0
0
30
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
30
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
30
10
0
0
0
0
0
10
10
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
20
10
0
20
0
0
0
0
20
10
10
0
0
20
20
% K
% Leu:
0
0
0
0
0
20
10
0
0
40
0
0
0
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
30
0
0
0
10
0
0
0
0
0
0
40
20
0
% N
% Pro:
0
10
0
0
0
20
10
40
0
10
10
0
10
0
0
% P
% Gln:
0
10
0
10
0
20
0
0
0
0
30
0
0
10
0
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
0
10
0
0
10
% R
% Ser:
0
0
10
10
20
20
50
20
50
0
20
50
30
0
10
% S
% Thr:
0
10
20
0
20
0
10
0
0
30
0
0
20
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _